The Company Agent sent to eliminate Lincoln carries a 92FS in "Scylla" (S4E01). Link (Dominic Purcell) takes his gun and shoots the Agent with it in the same episode. Feng's bodyguards are also carrying Berettas in "Quiet Riot" (S4E11). Fernando Sucre (Amaury Nolasco) uses a 92FS during Season 4; he holds it on General Krantz and his bodyguard in "Selfless" (S4E12). In "Deal or No Deal" (S4E13), he holds a 92FS on Sooter. Ferguson (Graham McTavish) has a 92FS in "Just Business" (S4E14). In "Going Under" (S4E15), he shoots at Gretchen several times. Scott (Titus Welliver) has a Beretta 92FS in "The Sunshine State" (S4E16). T-Bag (Robert Knepper) holds a 92FS in "The Mother Lode" (S4E17). Cpt. Hutchinson (Michael McGrady) has a 92FS in "Cowboys and Indians" (S4E20). Michael (Wentworth Miller) uses a 92FS in "Killing Your Number" (S4E22). His Beretta jams when he shoots it.
Don Self (Michael Rapaport) and Miriam Holtz (Shannon Lucio) kill Feng and his bodyguards with Beretta 92FS Non Guns in "Selfless" (S4E12). The Representative (Titus Welliver) uses a Non Gun 92FS in "Going Under" (S4E15). When the Priest (Daniel Zacapa) takes T-Bag's 92FS, it becomes a Non Gun in "The Mother Lode" (S4E17).
Gretchen (Jodi Lyn O'Keefe) holds a Colt Mustang on General Krantz in "Greatness Achieved" (S4E09). In "Selfless" (S4E12), she tries to kill T-Bag with the Mustang. In "Going Under" (S4E15), she fires it at Sucre till the gun runs dry.
Wyatt (Cress Williams) uses a suppressed Glock 17 in "Scylla" (S4E01). In "Shut Down" (S4E03), Wyatt kills Bruce Bennett with his Glock 17. ICE Homeland Security Investigations Special Agent Donald "Don" Self (Michael Rapaport) carries a Glock 17 as his service weapon; most notably in episodes "Eagles and Angels" (S4E04), "Quiet Riot" (S4E11), and "Deal or No Deal" (S4E13). General Krantz (Leon Russom) holds a Glock 17 on Gretchen in "Quiet Riot" (S4E11). Sooter (Kirk B.R. Woller) has a Glock 17 in "Deal or No Deal" (S4E13). Lincoln uses Sooter's Glock in the same episode. FBI Agent Wheeler (Jason Davis) carries a Glock 17 in "Going Under" (S4E15). Michael (Wentworth Miller) is seen with a Glock 17 in "The Sunshine State" (S4E16). A hitman (Joe Sabatino) sent to kill Michael uses a Glock 17 in "The Mother Lode" (S4E17). Ralph Becker (Raphael Sbarge) and Downey (Ted King) are seen with Glock 17's in "S.O.B." (S4E19) and "Cowboys and Indians" (S4E20). Agent Hooks (Ian Bohen) also has a Glock 17 in "Cowboys and Indians" (S4E20). General Krantz (Leon Russom) holds a Glock 17 on T-Bag in "Killing Your Number" (S4E22). Sara (Sarah Wayne Callies) shoots Christina with a Glock 17 in "Killing Your Number" (S4E22).
Michael (Wentworth Miller) threatens to kill Gretchen with a Glock 19 pistol in "Scylla" (S4E01). In a flashback, Gretchen (Jodi Lyn O'Keefe) holds a Glock 19 in "Breaking and Entering" (S4E02). Clozza (Dylan Kenin) holds a suppressed Glock 19 on Lincoln in "Eagles and Angels" (S4E04). FBI Agent Lang (Barbara Eve Harris) has a Glock 19 in "Going Under" (S4E15). Christina Scofield (Kathleen Quinlan) uses one in "Killing Your Number" (S4E22).
T-Bag (Robert Knepper) kills Sandinsky with a Glock Non Gun in "S.O.B." (S4E19). The Non Gun is standing in for a Glock 17, that Becker gave T-Bag. Christina Scofield (Kathleen Quinlan) uses a suppressed Glock Non Gun in "Cowboys and Indians" (S4E20).
In "Blow Out" (S4E06), Gretchen (Jodi Lyn O'Keefe) retrieves a Kahr K9 from her sister's house. Later in the same episode, she confronts T-Bag with the Kahr.
An M1911A1 is wielded by Homeland Security Agent Herb Stanton (Michael O'Neill) in "Deal or No Deal" (S4E13). One of the Priest's guards has an M1911 variant in "The Mother Lode" (S4E17).
Wyatt (Cress Williams) is seen assembling a SIG-Sauer P226 in "The Price" (S4E08). When he shoots Roland, the P226 becomes a Non Gun (see below). Lincoln (Dominic Purcell) carries a P226 in Season 4, most notably in "Selfless" (S4E12), "Going Under" (S4E15), "The Sunshine State" (S4E16), and "Cowboys and Indians" (S4E20). C-Note (Rockmond Dunbar) has a P226 in "Killing Your Number" (S4E22).
Wyatt (Cress Williams) "kills" Gretchen with a SIG-Sauer P22X Non Gun in "Scylla" (S4E01). In "The Price" (S4E08), Wyatt shoots Roland with a Non SIG three times.
Alexander Mahone (William Fichtner) is given a Smith & Wesson 5906 by his ex-wife in "Safe and Sound" (S4E05), and uses it as his sidearm for several episodes in Season 4. Mahone is seen with the 5906 twice in "Five the Hard Way" (S4E07). He also uses it in "Selfless" (S4E12). In "The Sunshine State" (S4E16), Mahone kills Scott with the 5906.
Theodore "T-Bag" Bagwell (Robert Knepper) carries a Springfield Armory Mil-Spec M1911-A1 pistol during Season 4. He is seen with it in numerous episodes, including "Five the Hard Way" (S4E07), "Deal or No Deal" (S4E13), and "Just Business" (S4E14).
Vikan's bodyguards carry Heckler & Koch MP5K submachine guns with Navy trigger groups in "Deal or No Deal" (S4E13). Several Company hitmen are armed with MP5K's in "Just Business" (S4E14). Some of these MP5K's have extended barrels (like the one seen in Season 2). Ferguson (Graham McTavish) tries to kill Michael with an MP5K in "The Sunshine State" (S4E16). Mahone finds a cache of MP5K's in "The Mother Lode" (S4E17).
Gretchen (Jodi Lyn O'Keefe) uses a Heckler & Koch MP5SD3 with Navy trigger group while holding the GATE office hostage in "Selfless" (S4E12). In the episode, despite being a trained killer, she inexpertly sprays from the hip rather than shoulder the weapon when shooting at the employee.
T-Bag (Robert Knepper) uses a suppressed Heckler & Koch G36C while holding the GATE office building hostage in "Selfless" (S4E12). Later Gretchen refers to the rifle as "MP5".
An assassin uses a scoped Ruger Mini-14 with a 20-round magazine in "S.O.B." (S4E19). Lincoln (Dominic Purcell) uses the same Mini-14 to shoot the door handle in "Cowboys and Indians" (S4E20).
Lincoln's sidekick uses a Remington 870 shotgun in a flashback in "The Price" (S4E08). The 870 is fitted with a pistol-grip and low-cap tubular magazine. One of Scott's bodyguards has a Remington 870 in "The Sunshine State" (S4E16).
Wyatt (Cress Williams) scouts a prison with a Remington 700PSS in "Breaking and Entering" (S4E02). One of Christina's snipers tries to kill Lincoln with a 700PSS in "VS" (S4E18).
An S.A.R. member uses a Ramo RT-37 37mm launcher with a side-folding stock to launch several gas grenades at the hotel in "Cowboys and Indians" (S4E20).
