Painkiller Jane is a 2007 science fiction action television series that ran for one season on the Sci-Fi Channel (now SyFy). Based on the comic book character of the same name, the series stars Kristanna Loken as the self-healing titular character DEA Agent Jane Vasco. The series' story was completely different from the 2005 film of the same name that starred Emmanuelle Vaugier as the title character. In both versions, the title character can heal from all mortal wounds and (apparently) cannot be killed except through complete destruction of the body (burned completely to ashes or explosion or acid) or dismemberment or decapitation.
The series was mostly filmed in Vancouver, British Columbia, but then abruptly moved to Budapest, Hungary for the last third of the season. To the show's credit, when the production moved to Hungary, the storyline also moved to the same country, so they did not try to make an Eastern European country look like the United States.
The following guns were used in the series Painkiller Jane:
In "Pilot" (E01), Riley Jensen (Sean O. Roberts) carries a Heckler & Koch Mark 23. A Mark 23 is also carried by a US Army MP in "Toy Soldiers" (E02).
Jericho 941 R Stainless
A thug in the pilot episode tries to shoot Jane with a stainless Jericho 941 R.
Jericho 941 R Two-Tone
In "Toy Soldiers" (E02), a CID (Criminal Investigations Division) Agent (Doug Chapman) wields a two-tone Jericho 941 R (stainless frame, matte blued slide).
Heckler & Koch VP70
A thug in "Pilot" (E01) pulls a Heckler & Koch VP70 out of his back holster to try to get the drop on Jane.
SIG-Sauer P226
In "Pilot" (E01), a "Neuro" makes police officers shoot at Jane Vasco. They all fire in a police station when, in the melee, the fire alarm goes off. They all use SIG-Sauer P226s.
Walther P99
Walther P99s are the standard service pistol for all guards and staff at the NICO facility in Budapest, used most prominently during the inmate insurrection in the season finale "Endgame" (E22).
Röhm RG 96
The Röhm RG 96, a blank-firing replica of the Heckler & Koch USP, is used by the Neuro hunting team, exclusively as their sidearm, during their time at the NICO facility.
Submachine Guns
Heckler & Koch MP5K
In "Pilot" (E01), a ten-year-old Jane Vasco (Tiera Skovbye) wields a Heckler & Koch MP5K.
Both Andre McBride (Rob Stewart) and Connor King (Noah Danby) carry Hungarian Kucher K1s when the NICO facility comes under attack in "Endgame" (E22).
Shotguns
Ithaca 37
In "Toy Soldiers" (E02), Connor King (Noah Danby) carries a stainless steel Ithaca 37 with a short barrel and an MP5K foregrip in place of the factory foregrip.
Rifles
Heckler & Koch SL8-4
In "Toy Soldiers" (E02), Andre McBride (Rob Stewart) uses a Heckler & Koch SL8 outfitted with a suppressor. The barrel has been threaded to accept a suppressor. This is an SL8-4, the Canadian or European version of the SL8 with short scope rail, double stack magazine well, with a flush fit 10 round magazine, Harris bipod, and scope. The rifle is wrongly depicted as capable of firing darts.
Machine Guns
RPD
Both Andre McBride (Rob Stewart) and Connor King (Noah Danby) use RPDs against rampaging escaped Neuros in "Endgame" (E22).
Browning M2HB
In "Toy Soldiers" (E02) undead soldiers use A Browning M2HB mounted on a Humvee.