Colombian National Police officers, including Horatio Carrillo (Maurice Compte), are armed with Beretta 92FS pistols. Various Sicarios also use Beretta pistols.
EKOL Dicle
The pistol used by "Poison" (Jorge A. Jiminez), Escobar's main Sicario, appears to be a blank firing EKOL Dicle with wooden grips.
EKOL Firat Magnum
José Rodríguez Gacha (Luis Guzmán) uses what appears to be a Beretta 92FS Inox with custom grips, notably in "Explosivos" (S1E06). Gacha's son also is seen with this handgun. This pistol is likely a blank-firing EKOL Firat Magnum.
Zoraki 914
The pistol carried by DEA Agent Javier Peña (Pedro Pascal) is a blank firing Zoraki 914.
SIG-Sauer P228 (Custom Nickel)
Pablo Escobar (Wagner Moura) uses a nickel SIG-Sauer P228 in several episodes of Season 1. A P228 customized with gold embellishments is held by Pablo during an encounter with Valeria Vélez (Stephanie Sigman) in "The Men of Always" (S1E03).
Star Model B
In "The Sword of Simón Bolivar" (S1E02), José Rodríguez Gacha (Luis Guzmán) uses what appears to be a nickel Star Model B pistol with custom grips to shoot his drug-sniffing dog after he loses a bet to Escobar.
Walther PPK
A Walther PPK is also carried by Pablo in Season 1.
Revolvers
EKOL Viper (Stainless)
Throughout Season 1, DEA Agent Steven Murphy (Boyd Holbrook) is seen using what appears to be the blank firing stainless steel EKOL Viper revolver in 2.5" barrel as his service weapon.
EKOL Lite
In the series premiere "Descenso" (S1E01), a Colombian officer pulls a snub revolver during a confrontation with Pablo Escobar in the police station. This revolver appears to be a snub blank-firing EKOL Lite.
The blank firing pistol Zoraki 925 in full automatic fire is another weapon seen prominently throughout the series in the hands of Cartel members and Sicarios.
EKOL ASI UZI
One of the most prominent weapons seen and used throughout the show is the blank-firing EKOL ASI Uzi. As with many weapons in the series, EKOL ASI UZIs are used as substitutes for the actual weapons used.
IMI Mini Uzi
Genuine IMI Mini Uzi submachine guns are seen in the hands of Sicarios, but are never fired.
Rifles/Carbines
IMI Galil AR
The IMI Galil AR is frequently used by members of the Colombian National Police, Colombian Army and Search Bloc Officers. Members of the M-19 guerrilla group also use Galil ARs during their attack on the Palace of Justice in Episode 4, "The Palace in Flames".
IMI Galil ARM
In period photos, Nicaraguan Sandinista rebels are seen with Galil ARM rifles.
M4A1 Carbine
The M4A1 Carbine is seen in the hands of predominantly the Colombian National Police, Colombian Soldiers, Search Bloc officers, and a few Medellin Cartel gunmen. In episode 6 "Explosivos" Colonel Corrillo (Maurice Compte) uses an M4A1 with suppressor and scope when finally cornering Medellin Cartel boss José Rodríguez Gacha. The M4 rifles are seen with a variety of accessories such as EoTech/Aimpoint/Trijicon sights, AN/PEQ-14 IR Designators, and Surefire Weapon lights. Given the fact that the series takes place in the mid 70's to early 90's with the earliest M4s not entering US military service until '94, both the accessories and weapons itself are highly anachronistic.
CQB-R/MK.18 Mod 0
Another anachronistic weapon that is seen throughout the series is the Mk 18 Mod 0 CQB carbine. The carbines are seen in the hands of DEA agents, Colombian Soldiers and Search Bloc officers. In the beginning of Episode 8 "La Grand Mentira" Colonel Carrillo (Maurice Compte) and Search Bloc officers are all seen with MK.18s while hunting for Escobar in the jungle.
Colt AR-15A2 Government Carbine
During the attempted rescue of the journalist Diana Turbay in "La Grand Mentira" (S1E08), Colonel Carrillo (Maurice Compte) uses a Colt AR-15A2 Government Carbine. Given that fact that this event takes place in the late 80's the weapon is one of the few that is appropriate for the timeline.
Heckler & Koch G3A3
In the series premiere "Descenso" (S1E01), DAS agents who stop Escobar at a roadblock wield Heckler & Koch G3A3 rifles. Colombian police officers are also seen with G3A3 rifles in other episodes.
M16A2
Colombian police officers use M16A2 rifles while raiding the hideout of José Rodríguez Gacha in episode 6, "Explosivos".
M16A4
Some of the Colombian police officers in episode 6 "Explosivos" also anachronistically use M16A4 rifles.
Shotguns
Franchi PA8
One of Gacha's men is armed with what appears to be a Franchi PA8 shotgun in the series premiere "Descenso" (S1E01).
Remington 870
Members of the Search Bloc along with Colonel Horacio Carrillo (Maurice Compte) use Remington 870 shotguns while confronting a group of Sicarios at a nightclub in the series premiere "Descenso" (S1E01).
Remington 870 (Folding Stock)
José Rodríguez Gacha (Luis Guzmán) uses a folding stock Remington 870 in the series premiere "Descenso" (S1E01).
Benelli M3 Super 90
When trying to intercept one of Escobar's carrier pigeons in "La Catedral" (S1E09), Javier Peña (Pedro Pascal) tries to shoot one of the birds down with what appears to be a Benelli M3 Super 90 12 gauge shotgun, but to no avail. Finally after handing the shotgun to partner Murphy (Boyd Holbrook), they are able to shoot down a pigeon and intercept one of Escobar's messages. The shotgun itself appears to be a non-firing prop and the muzzle flashes are CG.
Machine Guns
M60E4/Mk.43 mod. 1
In "Explosivos" (S1E06), a crewman aboard a police helicopter fires what appears to be an M60E4/Mk.43 mod. 1 MG while pursuing a fleeing José Rodríguez Gacha (Luis Guzman). A member also carries the machine gun while on the ground. As this episode is set in 1989, the use of this particular weapon is anachronistic.
Launchers
Mk 153 SMAW (Mockup)
Gacha uses a Mk 153 SMAW launcher to blow up a car in "There Will be a Future" (S1E05). He later uses the launcher against police forces in "Explosivos" (S1E06). Upon closer inspection, the launcher appears to be a mockup.