A SIG-Sauer P226 is carried by Gabriel Vaughn (Josh Holloway) as his sidearm, first seen in "Pilot" (S1E01). A nickel-plated variant is seen in the hands of a Mexican drug cartel gunman in the middle of "Rescue" (S1E05). Luther Vick (Ronnie Blevins) takes one from an unconscious black ops commando and tries to shoot himself in the chin in order to avoid being apprehended near the end of "Patient Zero" (S1E06). Ex-Chechen guerrilla fighter Jano (Dean Chekvala) is forced to use a P226 when he was ordered to create a neurotoxin bomb in "Cain and Gabriel" (S1E10).
SIG-Sauer P226R
A Black ops commando working for General Greg Carter in "Patient Zero" (S1E06) uses a SIG-Sauer P226R when he confronts Gabriel and Riley in Cedar Park, Texas.
Mei Chen (Faye Kingslee) uses a Beretta 92FS Inox as her sidearm, first seen in "Mei Chen Returns" (S1E03).
Beretta Px4 Storm
A drug cartel gunman is armed with a Beretta Px4 Storm before being disarmed and killed in "Rescue" (S1E05). A Novyi Svit Revolyutsioneriv terrorist briefly uses one in the middle of "The Grey Hat".
A Heckler & Koch Mark 23 was used as the main sidearm of John Norris (Matt Gerald) throughout "Delta Force" (S1E08) with and without a suppressor mounted.
Heckler & Koch USP
A drug cartel gunman is seen armed with the Heckler & Koch USP in the middle of "Rescue" (S1E05). Gabriel, during his time as a Delta Force commando, uses a USP chambered in .45 ACP in "Delta Force" (S1E08).
Kimber Warrior
Beginning in "Red X" (S1E02), Gabriel begins to carry a Kimber Warrior as his main sidearm to replace his P226.
M1911A1
A M1911A1 with pearl grips was seen in the shoulder holster of a MSS agent killed by Gabe in "Pilot" (S1E01).
Glock 17
The Glock 17 appears throughout the season as a frequent pistol in 2nd and 3rd generation variants, notably in the hands of USCC members as their standard pistol instead of the M9.
IMI Jericho 941
A few MSS agents are armed with the IMI Jericho 941, first seen in "Pilot" (S1E01) with Gabriel taking one for himself after being captured. Eric Hansen (John Pollono) uses a stainless steel IMI Jericho 941 in "Cain and Gabriel" (S1E10).
Walther P99
Jin Cong (Will Yun Lee) uses what appears to be a Walther P99 when threatening Riley in "Pilot" (S1E01).
Revolvers
Smith & Wesson Model 28
A Smith & Wesson Model 28 was used in the middle of "Being Human" by both Gabriel & Mrs. Vaughn (Debra Mooney) to take on Thomas Olivier.
Submachine Guns
Heckler & Koch MP5A2
A Black ops commando working for General Carter in "Patient Zero" (S1E06) uses a Heckler & Koch MP5A2 to fend off Gabriel in Cedar Parks, Texas.
Heckler & Koch MP5A4
A Black ops commando masquerading as a US Army soldier uses a Heckler & Koch MP5A4 in "Patient Zero" (S1E06) when his team apprehends Gabriel and Riley with a restrained Luther Vick. He is later disarmed with Riley later using the weapon to apprehend Luther again in the same episode.
Heckler & Koch MP5SD6
Rogue MSS agents led by Jin Cong disguise themselves as American soldiers while being armed with Heckler & Koch MP5SD6 submachine guns in "Athens" (S1E09). Nelson and Riley arm themselves with the SD6 after they disarm the agents guarding them.
Heckler & Koch MP5K
A few Mexican drug cartel gunmen are armed with the Heckler & Koch MP5K in "Rescue" (S1E05).
IMI Micro Uzi Pistol
A MSS agent in Maryland uses an IMI Micro Uzi pistol when confronted by Gabriel and Riley in "Pilot" (S1E01).
Assault Rifles
AK-47
AK-47s are seen in the hands on Indian soldiers stationed at the Himalayas near the Indian-Pakistani border in "Pilot" (S1E01).
AKM
Syrian Army Republican Guard soldiers are armed with AKMs as their main assault rifle in "Secrets of the Secret Service" (S1E04).
AKMS
In "Pilot" (S1E01), Gabriel brings up a rendering of the 2008 Mumbai terrorist attack where Lashkar-e-Taiba gunmen wield AKMS rifles.
Colt M4A1
The Colt M4A1 is also seen used as the main assault rifle for American law enforcement and military personnel.
Colt Model 933
Colt Model 933s are used by Cyber Command tactical team operators throughout the season.
IMBEL M964 A1 ParaFAL
IMBEL M964 A1 ParaFALs are seen throughout "Delta Force" (S1E08) in the hands of various characters in La Paz, Bolivia.
IWI Galil MAR
Some of the drug cartel gunmen are armed with IWI Galil MAR rifles in "Rescue" (S1E05). Gabriel later takes one of them for himself and uses it near the end of the same episode.
Norinco QBZ-97
MSS agents operating in Maryland are armed with QBZ-97s as their main assault rifle, first seen in "Pilot" (S1E01).
Norinco QBZ-97B
In addition to the aforementioned QBZ-97, MSS agents can also be seen using the QBZ-97B carbine while operating in Maryland, first seen in "Pilot" (S1E01).
Noveske N4 Diplomat
Noveske N4 Diplomat assault carbines are used by Riley and Secret Service agent Charlie Griffin (Michael Trucco) to rescue a CIA agent from Syrian Army Republican Guard soldiers in the middle of "Secrets of the Secret Service".
Zastava M70B1
Some Indian soldiers in "Pilot" (S1E01) are armed with Zastava M70B1s as their main assault rifle.
Zastava M70AB2
Some of the Indian soldiers chasing after Gabriel in "Pilot" (S1E01) are armed with Zastava M70AB2s.
Shotguns
Kel-Tec KSG
A Kel-Tec KSG is used by some Novyi Svit Revolyutsioneriv (NSR) terrorists throughout "The Grey Hat" (S1E11).
Over and Under Shotgun
Over and Under Shotguns are used near the end of "Being Human" (S1E13).
Serbu Super Shorty
A NSR terrorist named Piotr is armed with a Serbu Super Shorty when he confronts Gabriel and Riley in "The Grey Hat" (S1E11).
Sniper Rifles
Blaser R93 LRS2
During a hostage rescue mission, Gabriel is armed with a Blaser R93 LRS2 to provide cover for Riley in "Rescue" (S01E05).
DRD Tactical Paratus-16-LR-B
A hired assassin uses a DRD Tactical Paratus-16-LR-B as a short-range sniper rifle in an attempt to snipe Gabriel and Mei near the end of "The Event Horizon" (S1E12).
M99
The M99 is seen in "Pilot" (S1E01) as a cyber-rendering image when Gabriel investigates something outside the Cassidy residence.
Remington 700PSS
A Remington 700PSS is possibly used by Mei Chen in "Mei Chen Returns" (S1E03).
Springfield M1A with JAE-100 Stock
What appears to be a Springfield Armory M1A outfitted with a JAE-100 Stock is used in "Pilot" (S1E01). This is likely the same rifle seen in Almost Human as both series are shot in Vancouver, Canada.
Machine Guns
Browning M2
A Browning M2HB is seen mounted atop a Marine Humvee in "Red X" (S1E02).
DShK
A DShK is seen mounted on a Syrian Army Republican Guard Land Rover near the end of "Secrets of the Secret Service" (S1E04).
Unknown
Grenades
Mk. 2
A Mk. 2 frag grenade is used in a Mexican jumping bean trap in "The Rescue".