Harry and the Hendersons is a 1987 comedy about a family who hits a Sasquatch during a hunting trip and takes him back to Seattle. The Sasquatch, who proves to be friendly and gentle, stays in the family's home in order to hide from the local authorities and a notorious French-Canadian Bigfoot hunter. The titular creature was played by Kevin Peter Hall (best known for playing the alien in the first two entries of the Predator franchise) and later inspired a 1991 sitcom television series.
The following weapons were used in the film Harry and the Hendersons:
A stainless Colt Python with a 4" brrel is the main sidearm of Jacques LaFleur (David Suchet). Twice in the film, LaFleur's Python is handled by Harry (Kevin Peter Hall).
Smith & Wesson Victory
A nickle plated Smith & Wesson Victory Model is used by a woman who confronts Harry in her home. Approximately ten years after World War II the British government released a large number of surplus sidearms into the civilian market. The government needed cash and it was hoped that the gun-mad Americans would scoop up the firearms. They weren't wrong. Many of the Victory model were purchased by American importers and rebored for 38 Special, but not all of them. They also cut many of the revolvers down to snubnose configuration. That particular modification removed the barrel lug and the locking bolt spring giving the S&W revolver a distinctive Colt appearance. Lee Harvey Oswald owned a converted Victory model and allegedly used it to kill Dallas Police Officer J.D. Tippit.
A Smith & Wesson Model 29 is visible in the display case at the Henderson & Sons hunting store when Jacques LaFleur (David Suchet) purchases ammunition. Ironically, a customer later asks George Henderson (John Lithgow) whether he has a "Clint Eastwood Magnum", referring to the Model 29.
Colt 1911 variant
An unknown stainless Colt 1911 variant is visible in the display case at the Henderson & Sons hunting store when Jacques LaFleur (David Suchet) purchases ammunition.
Rifles
Steyr-Mannlicher SSG PII
A Steyr-Mannlicher SSG PII with double-set triggers is the main weapon of Jacques LaFleur (David Suchet) throughout the movie. Strangely, at one point in the film, he purchases .458 Winchester Magnum ammunition for the rifle, even though the SSG would not be able to chamber these rounds. Due to a continuity error, the SSG repeatedly goes from having a standard 5-round magazine to a 10-round box magazine in the final scene of the film when LaFleur is hunting Harry in the woods.
Winchester Model 70
A scoped Winchester Model 70 is George Henderson's (John Lithgow's) main rifle throughout the movie, and is nearly used to kill Harry (Kevin Peter Hall). Due to a continuity error, it is briefly replaced by another (unknown) rifle in a closeup where George pokes Harry's hand with the barrel of the rifle. The Winchester also has a diopter sight during the scene where George nearly shoots Harry, even though it did not have this feature in earlier scenes.
M16 (SP1)
M16 rifles are used by the SWAT team during the scene where the police chase Harry through Seattle. It is hard to tell, but the weapons may actually be MGC M16 replicas, since they are not seen clearly and are never fired. During one scene in the sporting goods store, a customer asks George Henderson (John Lithgow) if he has
"an M16, or anything that goes fully automatic", to which George replies that "fully automatic is illegal".
Shotguns
Mossberg 500AT
Mossberg 500AT shotguns are used by most of the police officers who pursue Harry through Seattle. It's hard to tell, but it appears that Jacques LaFleur (David Suchet) also uses a Mossberg 500AT briefly while tracking Harry.