A Colt M1911 is used by the character Dr. Edwin Lindsey in 1983 AD, called the "Automatic Pistol" in game. Paul Augustine also uses this pistol in a brief cutscene at the beginning of the chapter.
Chamelot-Delvigne Mle. 1874
A Chamelot-Delvigne Mle. 1874 is used by the character Peter Jacob in 1916 AD, called the "Revolver" in game. Oddly enough, the game describes its as Mle 1892.
Enfield Mk1 Star Revolver
An Enfield Mk1 Revolver is used by Dr. Edward M. Roivas in 1952 AD, called the "Revolver" in game.
Although the Enfield's description correctly identifies it as being chambered in .380/200, its ammunition comes in the same boxes as the .38 Special rounds from Alex's time.
Glock 17
A Glock 17 is used by Michael Edwards in 1991 AD, called the "Pistol" in game.
Shotguns
Remington Model 870
This Remington M870 is used by the character Dr. Edwin Lindsey in 1983 AD, called the "Shotgun" in game.
Ithaca Auto & Burglar Model A
An Ithaca Auto & Burglar Model A double-barreled shotgun is used by Dr. Edward M. Roivas in 1952 AD, called the "Double Shotgun" in game.
Winchester Model 1300 Ranger
A Winchester Model 1300 Ranger is used by Alex Roivas in 2000 AD, called the "Shotgun" in game. It is described as "Defender", but in fact this is a field "Ranger" variant.
Rifles
Lee-Enfield No. 4 Mk I
A Lee-Enfield No. 4 Mk I is used by Peter Jacob in 1916 AD, called the "Rifle" in game. In the game, this is described as the corresponding Mk.III model, but the rifle itself seems to be based on a later No.4 Mk.I.
Holland & Holland Rifle
A Holland & Holland Double Rifle chambered for .500 Nitro is used by Dr. Edward M. Roivas in 1952 AD, called the "Elephant Gun" in game.
XM29 OICW
A H&K OICW is used by Michael Edwards in 1991 AD, called the "Assault Rifle" in game.