The Losers is a 2010 action film based on the DC Vertigo comic and starring Jeffrey Dean Morgan as the leader of a Special Forces team who are determined to root out the CIA operative who betrayed them.
The following weapons were used in the film The Losers:
One of the handguns that Aisha (Zoe Saldana) uses is a Beretta 92FS. Security guards at Goliath Industries and Cryon Security Contractors also use Beretta 92FS pistols.
Beretta 85F Cheetah
The other handgun that Aisha uses is a nickel Beretta 85F.
A Desert Eagle is the main sidearm of Roque (Idris Elba). Judging by the pictures below, Roque's Desert Eagle switches between a two-tone version with a silver frame, and an all-black version.
[NOTE: this is not Roque's. pooch makes a bet, using this gun}
Taurus 44
A Taurus 44 is one of the guns that are bet when the Losers play cards at the beginning of the film.
The Taurus 44 is a .44 magnum 6 shooter, while the Taurus 608 is a .357 magnum 8 shot revolver, built on the same frame as the 44. It's a large-framed revolver and can be easily mistaken for the more well-known Taurus Raging Bull. As can be seen in the screenshots below the extra cylinder locking catch of the Raging Bull isn't visible, the barrel profile is different (the Raging Bull has a tear drop profile) and the vents of the Raging Bull are not present. On top of that, it can clearly be seen that the words "Raging Bull" are not present on the barrel.
Glock 17
A Glock 17 can be briefly seen in the hands of a member of Max's protection force during the armored car heist.
Heckler & Koch USP
Max (Jason Patric) is seen with what could be a USP to execute a scientist.
Shotguns
Remington 870
A Remington 870 shotgun fitted with a pistol grip, shell holder, and door breach break is used by Pooch (Columbus Short) during the harbor shootout.
A Knight's Armament SR-25 is the main sniper weapon of Cougar (Óscar Jaenada). He later uses another SR-25 equipped with a PRS stock after getting back to the US.
M4A1
The M4A1 carbine is carried by various members of the Losers including Jensen (Chris Evans), Pooch (Columbus Short), Roque (Idris Elba) and Clay (Jeffrey Dean Morgan) throughout the movie kitted out with different attachments depending on the mission. Several of Max's guards in the convoy also are armed with M4A1s.
Knight's Armament SR-15 E3 IWS
Other members of Max's protection force are seen defending the convoy with Knight's Armament SR-15 E3 IWS rifles.
AKM
The soldiers of Bolivian drug lord Fadhil (Peter Francis James) are armed with AKM assault rifles.
Heckler & Koch G36K
Some of the guards protecting Max's convoy in Miami are armed with Heckler & Koch G36K rifles with top rails and foregrips. This is also the gun Clay uses in his confrontation with Max.
FN SCAR-L
Cryon private security contractors at the Los Angeles harbor use FN SCAR rifles when they capture the Losers.
Clay (Jeffrey Dean Morgan) uses a stand-alone M203 grenade launcher with a M4-style stock, vertical handgrip, and C-More red-dot sight to fire a smoke grenade during the ambush of Max's convoy.
M136 AT4
Aisha fires an M136 AT4 from the hip, which is NO way to handle it. However, as Jensen notes, it makes Aisha look like "one bad-ass chick".
Other
Custom Rocket Launcher
An improvised rocket launcher is constructed and fired by Pooch (Columbus Short).
Crossbow
A crossbow is used by Jensen (Chris Evans) during the armored car ambush.