In Season 2's "Euphoria, Part 1", Baby Shoes (Chioke Dmachi) uses a Ruger SP101 to shoot officer Joe Luria (Scott Michael Campbell) during the opening chase. Dr. Gregory House (Hugh Laurie) tests a theory by using a similar Ruger SP101 revolver with a spurred hammer to shoot an already deceased cancer victim in the head and putting the body in an MRI machine with destructive consequences. The SP101 makes another appearance when author Alice Tanner (Amy Irving) uses one in a suicide attempt in Season 7's "Unwritten" (S7E03).
In Season 2's "Euphoria, Part 1", Officer Joe Luria (Scott Michael Campbell) is seen drawing his Glock 17 on a suspect at the opening of the episode. In Season 5's "Last Resort", Jason (Željko Ivanek) uses this third-generation Glock to hold Dr. House (Hugh Laurie), "Thirteen" (Olivia Wilde) and several patients hostage.
In Season 6's "The Down Low" (S6E10), a thug named Tommy (Preston James Hillier) pulls an H&K USP on Mickey (Ethan Embry), who is soon to become House's patient. Mickey wrestles the USP and gets Tommy to shoot himself in the foot, and the loud sound makes Mickey pass out.
L.K. (Brett Wagner) uses an M1911A1 in a diner robbery in Season 3's "Fools For Love" (S3E05). In Season 8's "Perils of Paranoia", Wilson finds House's M1911A1, which House succeeds in convincing Wilson is a prop, despite the fact that the cartridge House chambers is clearly not a blank.
Police officer Donny Compson (Jon Seda) and his partner (Jeff Corbin) carry SIG-Sauer P228s when chasing a suspect in Season 6's "Brave Heart" (S6E05).
The M4A1 carbine is seen in the hands of Marine Sgt. John Kelley (Marc Blucas) in Season 3's "Top Secret" and carried by SWAT officers in Season 5's "Last Resort".
In Season 3's "Top Secret", House is seen holding an M16A2 rifle, fitted with an ACOG scope on the carry handle and a RIS handguard in place of the standard A2 handguards in a dream sequence.
Error creating thumbnail: File missingIn Season 3's "Top Secret", House is seen holding an M16A2 fitted with the ACOG scope. Note that he appears to be wearing body armor with an ACU pattern while his uniform is in Marine MARPAT (however, this is a dream sequence).
In Season 6's "Wilson" (S6E09), Wilson (Robert Sean Leonard) and Tucker (Joshua Malina) are seen turkey hunting with Remington 870 Express shotguns. Wilson using a 12-gauge with a red dot sight and turkey camo, and Tucker with a 20-gauge and wooden furniture.
In Season 7's "Bombshells", House is seen turning his cane into what appears to be a Mossberg 500 Cruiser shotgun fitted with a pistol grip and weaponlight in a dream sequence.
