Throughout season 4 Det. Mac Taylor (Gary Sinise), Det. Don Flack (Eddie Cahill), Det. Jessica Angell (Emmanuelle Vaugier), Dr. Sheldon Hawkes (Hill Harper) and Det. Danny Messer (Carmine Giovinazzo) all carry Glock 17s. Also, any NYPD officer seen with a pistol is using a Glock 17 unless otherwise indicated on this page.
In "Can You Hear Me Now?" (S04E01), Charles Price (Erik Fellows) (one of the guards at the Statue of Liberty) is seen with a Glock 17 during a flashback.
In "Admissions" (S04E18), Inspector Stanton Gerrard (Carmen Argenziano) uses a Glock 17 to kill the man who raped his daughter.
Throughout season 4, Det. Stella Bonasera (Melina Kanakaredes) and Detective Lindsay Monroe (Anna Belknap) carry a Glock 26 as their sidearm. On at least one occasion Bonasera is seen with a Glock 19 instead.
Colt Commander
In "Down the Rabbit Hole" (S04E05) and "DOA for a Day" (S04E15), an assassin known as "Suspect X" (Kam Heskin) carries a Colt Commander with chrome finish, pearl grips, and a suppressor as her main weapon of choice. She notably uses it to kill a Congressman and later shoots a hostage to facilitate her escape. In "DOA for a Day" notably when she gets into a gunfight with Mac in the climax of the episode, using it until she is wounded in the chest by a round from Mac's Glock 17.
In "Hostage" (S4E21), a bank robber named Ethan Scott/Douglas Anderson/'Joe' (Elias Koteas) can be seen armed with an M1911A1 pistol as his main weapon.
Smith & Wesson 6904
In "Buzzkill" (S04E08), a kidnapper is seen with a Smith & Wesson 6904 pistol. When Mac and Danny close in to arrest the kidnapper, the gun is seen on a nightstand.
Walther PPK
In "The Deep" (S04E02), a Walther PPK is seen in Zamir Duka's bag.
Walther PPK (Stainless)
At the beginning of "You Only Die Once" (S04E03), Det. Flack (Eddie Cahill) is seen carrying a stainless Walther PPK.
Unknown 1911
In "Down the Rabbit Hole" (S04E05), Johnny O'Dell drops an unknown 1911 which Dr. Hawkes (Hill Harper) is later seen test firing.
Unknown Pistol 1
In "DOA for a Day" (S04E15), "Suspect X" is seen hiding an unknown pistol.
These are clearly two different guns. On the first picture it is most likely a Walther P5 due to the missing ejection port on the right side of the gun.The one on the second photo seems to be a clone of a Beretta 92 like the Taurus PT 99 or the Vector SP 1. --Fragery 15:32, 20 March 2012 (CDT)
H&K USP
In "DOA for a Day" (S04E15), Danny recovers a different pistol that was hidden by "Suspect X".
This gun is a H&K USP chambered in 9mm or .40 S&W as the barrel in the ejection port is plain with the slide while it lays a little lower in the .45 ACP version. The gun has an supressor attached probably making it an H&K USP SD 9, the 9mm Version of the USP Tactical which comes in .45 ACP and with a threaded barrel.--Fragery 15:37, 20 March 2012 (CDT)
Revolvers
Ruger GP100
In "The Thing About Heroes..." (S04E10), Drew Bedford (Kerr Smith) kidnaps Mac and puts him in a chair with a stainless Ruger GP100 pointed at him. Surrounded by lasers, if Mac moves, he will be shot. Mac manages to trigger the device so that it shoots Drew and then grabs the gun shooting him in the arm with it a second time.
Smith & Wesson Model 10
In "Child's Play" (S04E11), a robber uses a snub nosed Smith & Wesson Model 10 during a robbery.
Smith & Wesson Model 15
In "The Thing About Heroes..." (S04E10), a young Mac Taylor is seen holding a Smith & Wesson Model 15 during a flashback.
In "Commuted Sentences" (S04E07), a woman armed with a Smith & Wesson Model 640 is killed when an attacker grabs her from behind, turning the gun on her and forcing her to be shot with her own weapon. The weapon is found by the CSIs at the crime scene.
Unknown Revolver 1
In "Commuted Sentences" (S04E07), Det. Danny Messer (Carmine Giovinazzo) is seen pulling his backup weapon from his ankle holster. He and Lindsay remove the bullets and use them, and a slingshot, to determine the trajectory of a bullet.
Submachine Guns
Heckler & Koch MP5A2
In "The Deep" (S04E02), ESU officers are seen with Heckler & Koch MP5A2s while detaining a terrorist attempting to blowup a dock.
In "Down the Rabbit Hole" (S04E05), an ESU officer is seen with a Heckler & Koch MP5A2 when searching for "Suspect X".
In "The Thing About Heroes..." (S04E10), ESU officers are seen with Heckler & Koch MP5A2s while searching for Drew Bedford.
In "Taxi" (S04E20), ESU members are again seen with the Heckler & Koch MP5A2 when detaining the taxicab killer.
TDI Vector
In "Hostage" (S04E21) , a TDI Vector (referred to as the Kriss Super-V) is determined to be the murder weapon after a victim is found with two bullets through the same entry wound. This is due to the weapon's unique recoil reduction system. Det. Stella Bonasera (Melina Kanakaredes) is seen test firing the gun with DHS Agent Brett Dunbar (Adam Baldwin). One the men who supposedly kidnapped the bank robber is also seen with the gun.
Machine Guns
M240B Machine Gun
In "The Deep" (S04E02), a U.S. Coast Guard patrol boat armed with a bow-mounted M240B machine gun is seen among Coast Guard and N.Y.P.D. air units and surface vessels sent to intercept a terrorist diver attempting to blow up a helipad on the bank of the Hudson river where a foreign dignitary is arriving.
Rifles
Colt M4
In "The Deep" (S04E02), USCG officers are seen with Colt M4s when detaining a terrorist.
Sniper Rifles
Remington Model 700P
In "Hostage" (S04E21), N.Y.P.D. SWAT snipers can be seen armed with Remington Model 700P sniper rifles during the hostage crisis at the bank.
In "All in the Family" (S04E13), a Steven's Arms Double Barrel Shotgun is identified as the gun used in two murders. It is first used to kill a Judge, then is thrown off a roof where it kills a woman after striking the side of the building and discharging. Lindsay is also seen test firing the gun.
Ithaca 37
In "Boo" (S04E06), an Ithaca 37 is identified as a murder weapon. Dr. Hawkes (Hill Harper) is seen test-firing the weapon.
Unknown Shotgun
In "DOA for a Day" (S04E15), Det. Jessica Angell (Emmanuelle Vaugier) is seen with an unknown shotgun during the hunt for "Suspect X".