Colt Sherrif's Model Single Action Army (3" barrel)
A seven-year-old Quick (Desi Arnez Hines II) uses Sugar Ray's Colt Sheriff's Model SAA revolver with a 3" barrel and nickel finish(which appears to have a sawn barrel) to fatally shoot a toothless gambler (Ji-Tu Cumbuka) in the forehead during the opening 1918 flashback.
Smith & Wesson Model 36
Quick (Eddie Murphy) draws a Smith & Wesson Model 36 from an ankle holster during his fight with Vera (Della Reese), using it to shoot her in the foot when she draws a razor. (The use of the Model 36, developed in 1950, is anachronistic for a scene set in 1938).
Quick (Eddie Murphy) carries two nickel Colt Model 1903 Hammerless pistols with pearl grips. He is first seen drawing them from the glove compartment in his car as he is being chased by Smalls' brother, but has them in a shoulder rig later that night when at Dominique's.
M1928 Thompson
Smalls' brother (Arsenio Hall) and one of his thugs load up M1928 Thompsons with drum magazines when preparing to ambush Quick. They end up using them to shoot Junior, one of his other thugs, and to shoot up a flower shop Quick is hiding in. One of Ray's men also holds one on Cantrone in the bank.
Smith & Wesson Model 10
Smalls' brother's driver fires a single shot from his Smith & Wesson Model 10 after each volley fired from the Thompsons at Quick in the flower shop, until Smalls' brother finally yells at him to stop.
Colt Model 1908 Vest Pocket
Quick finds a nickel Colt Model 1908 Vest Pocket under Dominique La Rue's (Jasmine Guy) pillow. Later in the night, Dominique draws the pistol to try and shoot Quick, but he had emptied it when she wasn't in the room.
Winchester Model 1897
The NYPD officers, including Sgt. Cantrone, who raid Sugar Ray's nightclub carry Winchester Model 1897 shotguns. Two of Ray's men, including Jimmy (Charlie Murphy, brother of Eddie Murphy) later hold '97s on Cantrone inside the abandoned bank before tying him up in the vault.