Inspector Harry Callahan's (Clint Eastwood) primary weapon as expected is his ".44 Magnum", the Smith & Wesson Model 29 with an 8 3/8" barrel. He comments in the film to his partner Insp. Kate Moore (Tyne Daly) that he particularly favors this gun do to penetration power, since he claims he's seen a .38 ricochet off a car windshield.
The 2" barrel version of Colt Python is carried by Callahan's partner, Inspector Kate Moore (Tyne Daly), who keeps it in her purse. This revolver is also carried by many members of the San Francisco Police Department.
Callahan's first partner in the film, Insp. Frank DiGiorgio (John Mitchum), carries a large N-Frame Smith & Wesson Model 27 with a 4" barrel as his sidearm.
The M16 and the M16A1 were used by the SFPD officers that arrest the Uhuru group, and later are seen among the weapons stolen from the Hamilton Firearms warehouse by Bobby Maxwell (DeVeren Bookwater) and his terrorist group, The People's Revolutionary Strike Force, who would later use them to abduct the Mayor (John Crawford) and hold him on Alcatraz.
The M72A1 LAW is seen in the film, and are among the weapons taken from the depot by Maxwell and his men. During the final battle on Alcatraz, Maxwell drops his and is picked up by Harry, who uses it to destroy the tower that Maxwell makes his last stand in. When Harry fires the weapon, it looks more like a flare that was used to substitute for the rocket.
A nun in the church Harry goes to at the end of the movie to investigate the priest tries to fire a Remington 870 Folding Stock on him before being killed by Inspector Kate Moore.
