In some scenes, Agent 86's SIG P226 changes into a SIG-Sauer P228 pistol instead.
SIG-Sauer P232
Agent 99 (Anne Hathaway) packs a SIG-Sauer P232 throughout the film and also on the film's promotional posters. The SIG P232 is the stainless version of the popular P230.
AKMS
An AKMS is seen in the hands of an Afghani guard making rude remarks about women as they pass, one of which is the wife of the man next to him. Another is seen in the hands of a guard in the nuclear weapons factory hidden inside the bakery.
Skorpion SA Vz 61
When Maxwell Smart/Agent 86 (Steve Carell) and Agent 99 (Anne Hathaway) infiltrate Ladislas Krstic's (David S. Lee) mansion, one of his guards holds a Skorpion SA Vz 61 on him before he is rather awkwardly dissarmed by 86. When the Skorpion gets knocked out of 86's hands, 99 kicks it up to him just in time to kill Krstic before he kills them.
AKS-74U
Krstic (David S. Lee) is seen using an AKS-74U when he tries to kill Agent 86 and Agent 99, before 86 kills him.
The Desert Eagle is the weapon of choice for Agent 23 (Dwayne Johnson). His model is the .44 Magnum Israeli model without the notches on the barrel and without the hooked decocking safety.
Beretta 92FS
Beretta 92FS pistols are seen several times in the film. The first instance is during the training simulation, in which Larabee (David Koechner) uses a Beretta loaded with SimTech paintball rounds. Later, Bruce (Masi Oka) is seen using one to hold on Agent 86 (Steve Carell), in order to trick the security cameras into thinking he truly is trying to capture him. Finally, Agent 86 grabs a Beretta from a display case in the CONTROL lobby, but never uses it.
Glock 17
A Glock 17 loaded with SimTech paintball rounds is used by Agent 91 (Terry Crews) during the training session.
SWAT team members are seen armed with M4A1 carbines fitted with TA31F ACOG scopes and tactical flashlights when they attempt to apprehend Agent 86 (Steve Carell), only to find Lloyd (Nate Torrence) dressed like him, who quickly faints at the sight of so many guns pointed at him.
On of Krstic's men fires an unknown pistol at Agent 86 (Steve Carell) and Agent 99 (Anne Hathaway) as they try to escape.
Colt Detective Special
Several Colt Detective Special snub nosed revolvers are seen in display cases in the CONTROL lobby. While not seen taking one, Agent 86 (Steve Carell) holds one on Agent 23 (Dwayne Johnson) while he tries to escape in his car.