FBI Special Agent Seeley Booth (David Boreanaz) carries a Glock 17 as his sidearm on the show. For a few episodes, starting with Season 1's "The Man On The Fairway" Booth's Glock is shown with a stainless slide.
In Season 4's "The Man in the Outhouse" (S4E03), a Glock 23 is taken as evidence. It is said to be .40 caliber, which combined with its compact size, narrow it down as a G23.
In the pilot episode, Dr. Temperance "Bones" Brennan (Emily Deschanel) uses what appears to be a Smith & Wesson Model 625 at an indoor shooting range and what may be the Non Guns model is used to wound a suspect in the leg.
A farmer owns it for protection and Cam is later seen shooting it (To "relive stress") into gel.
Smith & Wesson Model 500
In Season 2's "The Man in the Cell" (S2E12), Dr. Temperance "Bones" Brennan (Emily Deschanel) begins carrying a 4" Smith & Wesson Model 500 that she claims to have bought at the mall. The impracticality of the large-caliber gun for the purposes of law enforcement becomes a running gag in the series. She and Booth both use the weapon in the final showdown with a murderer in Season 3's "Mummy in the Maze" (S3E05). The killer mentions in the episode that the .50 caliber 500 only holds 5 shots, and Booth takes advantage of its power to shoot through a metal door.
In Season 4's "The Con Man in the Meth Lab" (S4E09), Brennan takes a Smith & Wesson SW1911PD Tactical Rail Series out of Booth's holster. It has a tactical rail on the frame nose.
In Season 3's "Mummy in the Maze", the murderer dressed as a clown uses a sawn-off double barrel shotgun in a shootout with Booth. Booth mentions how a military man can miss with a scattergun.
Error creating thumbnail: File missingThe weapon in the episode was sawn down to the semi-pistol grip portion of the stock with the barrels left relatively long, similar to this weapon - 12 gauge.Error creating thumbnail: File missingIn Season 3's "Mummy in the Maze", the murderer dressed as a clown uses a sawn-off double barrel shotgun in a shootout with Booth.
Double Barrel Shotgun
In Season 5's "The X in the File" (S5E11), a rancher woman uses a Double Barrel shotgun loaded with rock salt to shoo people off her land.
The M4A1 is seen carried by US Army troops in Season 1's "The Soldier on the Grave".
Booth is seen carrying and firing an M4 with a Laser aiming module, Red dot sight, surefire torch and a front grip in Afghanistan in episopde one of series six
An U.S Army honor guard is shown with M1 Garand rifles in both Season 1's "The Soldier on the Grave" and when Booth is seen as part of another honor guard.
In Season 4's "The Princess & The Pear", a Winchester Model 1892 is seen hanging on Booth's mantle in his apartment.
Error creating thumbnail: File missingThe Winchester 1892 Saddle Ring Carbine with large lever loop used by John Wayne in the film True Grit. Serial #501892. Pictured with .44-40 shells. (Source: Photocopied from book "The Peacemakers: Arms and Adventure in the American West" written by R.L. Wilson.)Error creating thumbnail: File missingIn Season 4's "The Princess & The Pear", a Winchester Model 1892 is seen hanging on Booth's mantle in his apartment.
Machine Guns
Browning M2
A Browning M2 HB is briefly seen mounted on top of a humvee in Season 1's "The Soldier on the Grave".
In Season 4's "The Man in the Meth Lab" (S4E09), a police instructor shows recruits how to use a stand alone M203 grenade launcher, which he fires into a broken down trailer. A body then erupts from the explosion and the episode's case begins.