Used by Sir John Talbot (Anthony Hopkins).It is possible that the rifle used in the movie is not a Holland & Holland Paradox and that the weapon thought to be a Paradox is actually an Eight Bore shotgun. See the discussion page.
Martini Henry Rifle
A professionally sporterized Martini-Henry Mk. III being used against The Wolfman by Dr. Lloyd (Michael Cronin). It can be identified as a Greener-modified gun by the large cocking lever.
Webley Mark VI
Used by Detective Aberline (Hugo Weaving) throughout the film, and chief of police Colonel Montford (Nicholas Day) in the gypsy camp. After Gwen (Emily Blunt) pushes him away, she takes the revolver and runs, at the end she uses it to shoot and kill The Wolfman.
British 1853 Enfield
Used by Abberline's men.
Winchester 1895 lever action
Used briefly by Lawrence Talbot (Benicio del Toro) during the gypsy camp attack. He brought it with him in his horse's saddle and shoots at the werewolf with it, but tosses it aside rescuing a woman and later appropriates a dead man's rifle.
Either .303 British or .405 Winchester
Probably the latter since Sir John Talbot was a big game hunter and the '95/ .405 combo was a favorite of hunters like Teddy Roosevelt.
Double Barrel Shotgun
Used by the men at the gypsy camp and at the trap with the deer in the forest.
Unknown Revolvers
Used by the police and by the locals in Blackmoor during the werewolf hunt.
Webley Bulldog
During the attack on the gypsy camp, Constable Nye (David Schofield) carries a Webley Bulldog. Later in the film, Abberline's partner Carter (Shaun Smith) carries a Bulldog as his sidearm in several scenes.
Winchester Model 1866 "Yellow Boy"
After scaring off some men from town who wanted to take Lawrence, Sir Talbot (Anthony Hopkins) puts his shotgun on the wall along with his other rifles, the one above his shotgun looks like a Winchester Model 1866 "Yellow Boy"
Unknown Rifle or Shotgun
Abandoning his own rifle, Lawrence takes a weapon off of a killed man during the gypsy camp attack and uses it in his pursuit of the werewolf.