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Resident Evil 4
Handgun (H&K USP-9)
Leon Kennedy's standard weapon. In the game the gun is two tone. It is also used by Albert Wesker in the Mercenaries Mini game, albeit equipped with a silencer.
Punisher (FN Five-seveN)
Based off of Fabrique Nationale's Five-seveN handgun which normally chambers the 5.7mm cartridge originally intended to pierce low-levels of body armor. The version seen in-game chambers regular 9mm Parabellum.
This weapon can be purchased from the Merchant, or won in a contest after shooting ten of sixteen blue targets scattered across two areas. If all targets have been shot, the Punisher will have a free upgrade added onto it, making it slightly more powerful than an unupgraded Handgun.
The gun is used by Ada in Assignment Ada and The Mercenaries, and by Leon in the main game.
Red 9 (Mauser C96 Red 9)
A 9mm version of the Mauser C96 handgun, one of the first automatic handguns to enter production in the world. The Red9 version was developed during World War I and chambered 9mm Parabellum to keep ammo supplies standard, but when soldiers began to load the weapon with the wrong type of ammunition, a large Red 9 was placed on the grip to differentiate the model from the standard Mauser.
This weapon can be purchased from the Merchant, along with a stock which improves its accuracy significantly.
Spaniard Luis Sera uses this as his sidearm in the main game.
Blacktail (Springfield Armory XD-9)
Purchased from the Merchant. Ada uses this as her sidearm in the main game and Seperate ways. Leon uses it in The Mercenaries.
Matilda (HK VP-70)
Unlocked to be purchased from the Merchant after successfully completing the Normal difficulty of the game. Fires three-round bursts. The gun's name is a reference to the movie Leon The Profesional.
Shotgun (Remington 870)
May be obtained in one of three ways. On Easy mode the weapon is in your inventory, on Normal modes or higher you may obtain it for free in the upstairs section of a house in the Ganados Village, or you may purchase this weapon from the Merchant.
Riot Shotgun (Benelli M4 Super 90)
May be purchased from the Merchant. The gun in the game is stainless steel. it is also used by Leon in the Mercenaries.
Striker (DAO-12 "Street Sweeper")
May be purchased from the Merchant.
Ada's shotgun (Mossberg 500)
Ada uses this shotgun in Separate Ways. The gun in the game is stainless steel and the action bar is in the pistol grip style.
Bolt Action Rifle (Springfield M1903A4)
A modified version of the Springfield rifle which fired .30-06 cartridges, while this version fires .223 caliber rounds. May be purchased from the Merchant.
Semi-Auto Rifle (H&K SL8)
May be purchased from the Merchant. This gun is also used by Ada in Seperate Ways, and Assignment Ada, and The Mercenaries, and by Wesker in The Mercenaries.
TMP (Steyr TMP)
May be purchased from the Merchant. A stock may also be purchased to improve accuracy and reduce recoil. HUNK uses a TMP modified with a fixed stock, foregrip, sawn off barrel, and laser sight in The Mercenaries. Krauser also uses this same modified TMP in his boss battle in the main game.
Chicago Typewriter (M1A1 Thompson)
Unlocked by completing the sidestory Separate Ways and may be purchased from the Merchant after that. If used with the Mafia costume, the gun is modified with a foregrip and a drum magazine.
Broken Butterfly (Schofield Model 3)
May be found in a section of the castle after freeing Ashley, or may be purchased from the Merchant.
Killer 7 (AMT Hardballer 1911)
May be purchased from the Merchant. Used by Wesker in the Mercenaries.
Handcannon (S&W Model 500)
Get a five-star rank with all characters on all stages (Mercenary Mode). When fully upgraded has infinite ammunition and deals the highest damage of any non-explosive weapon in the game. The in-game weapon is equipped with a laser sight.
Minethrower
May be purchased from Merchant. The weapon fires custom darts with explosive tips that embed themselves in an enemy and detonate after a period of time. When fully upgraded its mines will automatically hone in on the nearest enemy.
Bow Gun
May be purcase from Merchant in Separate Ways. The weapon has a pistol grip and fires explosive arrows.
Rocket Launcher/Special Rocket Launcher/Infinite Launcher (RPG-7)
The standard Rocket Launcher may be purchased any time from the Merchant, or you will find one in the Castle. The Special Rocket Launcher is a special-event item. The Infinite Rocket Launcher is available for purchase from the Merchant upon completion of the game once.
Krauser's Bow
Krauser uses this weapon in Mercenaries minigame. In the main boss battle it fires explosive arrows.
Plaga Removal Laser(P.R.L.) 412
Availible after beating game in Professional mode. The weapon uses a light based laser to dissolve the Plaga in a person without harming the host.
GE M134 Minigun
Used by a senior monk of the Las Plagas cult in the Castle section of the game. Cannot be used by the player.
Los Illuminados Gatling Gun
This gun is used by J.J. (The minigun wielding Gannado) and cannot be used by the player.