Colombian National Police officers, including Horatio Carrillo (Maurice Compte) as well as DEA Agent Steven Murphy (Boyd Holbrook) are armed with Beretta 92FS pistols. Various Sicarios also use Beretta pistols.
In "The Good, the Bad, and the Dead" (S2E04), Pablo loads a 9mm bullet given to him by a child into a Jericho 941 and uses it to shoot Carrillo. In other camera angles, this pistol changes to a Beretta 92FS.
A Colombian police officer is armed with what appears to be a Colt Python with 6" Barrel in "Los Pepes" (S2E06). It's possible that this also is a replica.
Another weapon that is introduced to in Season 2 is the Galil ACE predominantly the ACE 21 and 23 variants. They are frequently used by Search Bloc Officers, Colombian Army Soldiers, Los Pepes, and Cartel members. The ACEs are seen with a variety of weapon attachments such as MOR B Reflex Sight, CAA FVG5 folding foregrips, rifle scopes and sound suppressors. Despite that fact that the Galil ACE is the standard service rifle for the Colombian Army and National Police, these rifles and accessories are highly anachronistic for the timeline the Season takes place since the ACE did not enter service until 2008.
Another anachronistic weapon that is seen throughout the series is the Mk 18 Mod 0 CQB carbine. The carbines are seen in the hands of DEA agents, Colombian Soldiers and Search Bloc officers including "La Grand Mentira" Colonel Carrillo (Maurice Compte).
The blank firing pistol Zoraki 925 in full automatic fire is another weapon seen prominently throughout the series in the hands of Cartel members and Sicarios.
An M60E3 is used by Colombian soldiers. When being introduced to the Castano Brothers in "The Good, the Bad and the Dead" (S2E04), Carlos Castano (Mauricio Mejia) is seen with an M60E3 while overseeing a brutal village raid in search of Communist Guerillas. The M60E3 is another one of the few weapons that is appropriate for the timeline in which this season takes place. The earliest M60E3 variants were fielded to US Military forces in 1986.