The weapons of choice for the main female character, Revy are twin modified Beretta 92FS model pistols, which are stainless steel and have a 5.9 inch barrel and slide configuration, 1 inch longer than any standard Beretta 92 model. They are engraved with "9mm Sword Cutlass", the Jolly Roger of the famous pirate Calico Jack (which is also inlaid into the ivory grips), and an inscription in Thai. Revy calls it the "Praiyachat Sword Cutlass Special". Due to Revy's ambidextrous marksmanship skills, she is nicknamed "Two Hands" by the people of Roanapur. One of the pistols is eventually destroyed after Revy fights Ginji in the conclusion of the second season.
Revy always wears her Cutlass pistols in double cross-draw shoulder holsters and almost always draws them simultaneously to lay down an incredible rate of fire. The magazines are the same stainless finish as the weapon, though it's not explained how exactly Revy carries them.
Smith & Wesson Model 629
This Smith & Wesson Model 629 is Dutch's sidearm throughout the series, which he is extremely proficient with. Notably, he is also a good hip-shooter.
Glock 17
Glock 17s are shown as the most prominent handgun for the Colombian Mafia during the first story arc featuring Garcia and Roberta and the bar scene in the first OVA.
Glock 17L
A Glock 17L is used by Sister Eda, who is part of a group called "The Church of Violence", an arms dealing racket. Strangely, in the close-up shots of Eda's gun, the signature Glock trademarks are missing.
Luger P08
An empty Luger is seen in the U-boat after the confrontation. It is bloodied and empty. Also, a heavily customized Luger P08 Artillery Model Pistol is used by one of the Neo-Nazis, Fritz Stanford. This unique Luger has a gold finish, an artillery length barrel and chambered for .454 Casull rounds. The Aryan soldier referred to the gun as "the Eiserne Reich Luger Special" (Eiserne Reich translates as "Iron Empire" in English). He also mentions features for the gun such as a "two bullet chamber" (a bad translation for "double-stack magazine"). He never fires it, but rather endlessly rants about its beauty to Revy, before she kills him.
Desert Eagle
The leader of the mercenaries in the first episode, is seen holding a MK VII Desert Eagle. Yolanda's the head nun of the Church of Violence uses one engraved, gold plated Mark I Desert Eagle. Despite being a huge, heavy and powerful handgun, she handles it like it was nothing.
Mauser C96 Type 712
Lotton/Rotton the Wizard carries dual Mauser M712 "Schnellfeuer" pistols. He is not see firing them, mostly missing his chance to use them on-screen, in favor of acting dramatic and what he sees fit as "cool".
Tokarev TT-33
Tokarev TT-33 Pistols were seen used by numerous characters, but primarily with the Russian Mafia, Hotel Moscow, and it is their standard sidearm. It is also seen used by the guerrilla Ibraha.
Stechkin APS
The Stechkin APS is Balalaika's sidearm throughout the series, and is also used by Yukio Washimine on full auto.
Makarov PM
During a split second flashback in the OVA, we see several individuals armed with Makarov PM pistols.
M1911A1
Multiple variants of the M1911A1 are seen several times in the series either up close by central characters or in the foreground by random thugs. Most appear blued and not Parkerized, and feature the full bar safety.
Sistema Colt Modelo 1927
Two of these are used solely by Roberta, a former FARC guerrilla trained as an assassin, who cleverly disguises herself as a maid do escape her old life of warfare and death. It makes sense for Roberta to carry Sistemas since she comes from South America. In the 4th OVA, Roberta attaches drum magazines to both her pistols during her fight with the US spec ops.
AMT Hardballer Longslide
Chang dual wields two (somehow blued and not stainless steel) AMT Hardballer pistols with extended slide assemblies. You figure that since he is an allegory for Chow Yun-Fat's various characters in John Woo Films, he'd have two Beretta 92FS Pistols, but then he'd be so close to the inspiration there might just be a lawsuit of some sort. Interestingly enough in the most recent chapters of the manga he even claims to be a former cop.
Beretta 76
For some odd reason, Mr. Chang wields two Beretta 76 .22 LR caliber handguns as he did with his AMT Hardballer Longslides when fighting off Gretel's assault on him. In the manga, these are described as being his personal weapons.
Ruger Blackhawk
A Ruger Blackhawk was used by Chaka, who fancied himself as some kind of wild west gunman. It was later destroyed when Ginji sliced it up with his superhuman strength and sword. From the looks of it, Chaka's Ruger has a rear end sight. In this case it is not a Single Action Army; it is Ruger's base on an SAA. A big lapse is that the weapon is fired in double action, with the hammer being cocked by the trigger pull.
Accu-Tek HC-380
This was used in the last episode once by Balalaika when she asked her Yakuza equivalent in Japan to oblige her with his guard's weapons. The second gun, an Accu-Tek HC-380 causes her to lose it as she calls it an "atrocious" gun. On closer inspection it looked like the artist drew "Picatinny Rails" along the top of the slide (which are actually anti-glare serrations). She kills the Yakuza boss and his guard with it, and tosses it to Rock as a gift, claiming it was a good weapon after all. Rock, the ever passive businessman, declines the gun, and thanks Balalaika for her deed.
Smith & Wesson Model 439
Revy started her life of crime at a young age. The series alludes to her being responsible for a murder in her past, and she also explicitly stated that she killed people as a kid. In one of her flashbacks she is seen using a Smith & Wesson Model 439 to shoot cans.
Walther P38
A Walther P38 was used by the SS officer in a flashback and found in the corresponding sunken submarine.
SIG-Sauer P226
A SIG-Sauer P226 is seen in the hands of a Hotel Moscow member during the Tokyo story arc. In the 4th OVA, First Sergeant Sanchez draws a P226 on Garcia when he attempts to shoot them, but is ordered to holster it.
MP-446 "Viking"
One of Hotel Moscow's soldiers uses a suppressed MP-446 "Viking" while hiding under a van with slashed tires.
Ruger P90
Abrego, the leader of the Colombian cartel carries and fires a Ruger P90 at Roberta in the "Maid to Kill" story arc. Much later in the series, Balalaika requests to see the Japanese Bodyguard's weapons in the final negotiation. He hands her his Ruger P90, with a grey finish and wood grips, similar to the ".45 Ruger" seen in an episode of Law & Order: Criminal Intent.
Browning Hi-Power
The Browning Hi-Power was seen briefly in the hands of a thug working for the Colombian Cartel. In the OVA, another member of the Cartel holds one at Fabiola, before getting shot with her MAG-7s.
"Pre-B" CZ 75
A "Pre-B" CZ 75 was seen in the hands of Takenaka in the first season finale, which inexplicably changes to a "First Model" CZ 75 during its last appearance. One of the Colombians is also seen shooting a "Pre-B" CZ 75 at Roberta (see the Browning Hi-Power entry above).
Solothurn ITM AT84S
Modern clone of the CZ-75, the Solothurn ITM AT84S pistols are seen in the Praiyachat gun shop. They are identifiable by the lack of milling-cuts on the dust-cover and their distinctive rear sight.
"First Model" CZ 75
Takenaka's "Pre-B" CZ 75 inexplicably changes to a short-railed "First Model" CZ 75 during one shot.
Single Action Army
One of the thugs at the Yellow Flag carries a Nickel plated Single Action Army.
Smith & Wesson Model 19/66
Other thugs in the Yellow Flag are seen with Smith & Wesson Model 19 and Smith & Wesson Model 66 revolvers. They are also seen used by "Groovy Guy" Russel in pursuit of Jane during the "Greenback Jane" arc.
Smith & Wesson Model 36
The Smith & Wesson Model 36 is used by Elroy to kill Gretel, under orders of Hotel Moscow. In the Second OVA, a random thug was seen threatening Revy and Fabiola with one. In the 4th OVA, Garcia was seen clutching this revolver he picked up, wanting to kill the leader of the NSA commandos, Major Caxton.
When confronting the twins, Verrochio pulls out a Bernardelli P-018 on them.
Walther PP
In the second OVA, a Walther PP was seen on the gunsmith's wall next to a Solothurn ITM AT84S.
Colt Walker Model 1847
A Colt Walker revolver can be seen above the Flintlock Rifle mounted above the Lovelace Family's fireplace.
Shotguns
Remington 870 Marine Magnum
Dutch uses a Remington 870 Marine Magnum when he and Revy assault a ship full of Aryan Socialist Union members in an attempt to retrieve a painting for a client. He wields this gun with tactical ease, reloading only after firing all seven rounds.
Remington 1100
Bao, the owner of the Yellow Flag owns a Remington 1100 Tactical model, which he uses to defend himself with every time his bar is shot up, which occurs regularly.
Fabiola Iglesias uses 2 South African madeTechno Arms MAG-7 shotguns in the OVA. For some reason, Fabiola's MAG-7s fire in semi-auto instead of pump action as that is how the real shotgun works and she's using buckshots. The scene where Fabiola takes out her MAG-7s, has a very Desperado feel to it, because it involves the Colombians dealing with someone deceivingly dangerous in a bar and the MAG-7s comes out of her sleeves.
Sub-Machine Guns
Uzi
The Uzi is one of the many type of common weapons used by thugs, mercenaries, mobsters, and gangs. In one episode it was prominently shown in the hands of security detail for one of the major mafia groups in Roanapur.
Heckler & Koch MP5A3
One of the Neo-Nazi's uses an Heckler & Koch MP5A3 to fire on Revy & Rock when they surface after escaping from the German submarine.
M3A1 "Grease Gun"
The M3 / M3A1 "Grease Gun" was seen in the last arc of the the series, where a drive by with Yakuza had used theses to attack a Russian restaurant. It is even possible these guns are old war relics left by American troops after World War II to the JSDF.
PM-63 RAK
She only used this in the 3rd episode. The Submachine gun she uses is a PM-63 RAK. It's a Polish made weapon that fires 9x18 Makarov PM.
MAC-10
The MAC-10 is another common weapon used by any random thug or mercenary or even the mafia groups.
PPS-43
Seen in the 2nd OVA, a PPS-43 was seen on the wall under an L86.
M1 Thompson
The M1 Thompson is seen in both the OVA and in the main series. Most notably in the Episode 16 "The Roanapur Freakshow Circus", where it is used by one of the thugs hunting for Jane.
Assault Rifles
AK-47
These are the weapons, obviously the AK-47, used by almost every faction in the entire anime. Symbolism to the obvious prolific nature of the infamous Assault Rifle, it has been used by all the factions. Balalaika's men during their services as part of the Russian special forces also used AK47s.
AK-74
Since all of Balalaika's men were Ex-Russian Paratroopers or elements of Special Forces, they would use AK-74s.
AKS-74U
Balalaika's ex-Russian Special Forces cadre aka the Vysotnoki (a mistranslation of the term "Desantniki", which is a Russian slang term for "Paratroopers") all used AKS-74Us during their operations in Japan. These were also seen in the hands of the mercs hired to get the data disk from Rock in the first episode.
APS Underwater Assault Rifle
An APS Underwater Assault Rifle was used once as one of those exotic 15 minutes of fame kind of guns that makes a "guest" appearance in an episode. This rifle was given to Revy from Dutch at the end of one episode for an underwater mission to retrieve a precious painting from a sunken Nazi submarine that ended up in the South Pacific. Revy fired the weapon inside the sub against the Neo-Nazis that also were after this prize. Since the weapon was designed to function both above and under water, the weapon was still able to function properly in the air-filled submarine. She later fired the gun underwater at two divers on the surface next to the pod, which is what the APS Underwater was designed for.
M16A1
In several scenes, we see random mercenaries in the background using M16A1s. On closer look, all of them are the kinds that were first seen in action during the Vietnam conflict. It makes sense since they are most likely mercenary groups in the South Pacific. After any major war, there is always surplus in arms supplies. During the flashback in the first OVA episode, US troops are seen using the M16A1, as noted with the forward assist on them.
M4A1 Carbine
In the OVA, the US Army NSA commandos (Grey Fox Unit) use the Colt M4A1 carbine as their primary weapons, outfitted with EoTech sights, flashlights, and suppressors when we first see them. It's interesting to note that Eotech didn't develop this particular sight until after 2001. It's interesting to note in the Japanese translation, they were referred to as "US Carbines" from their gun fire, but in the English dub, they were called "M4 Carbines".
Battle Rifles
Heckler & Koch G3A3
The Heckler & Koch G3A3 was first seen in the first episode when Revy tossed one to Rock to use to defend himself. He didn't know anything about guns and refused. After a heated battled with a Hind helicopter, in a fit of rage, he threw the rifle in the air and into the ocean, pissing off Revy because it must have cost her plenty. G3 rifles have been seen in the hands of Triad boss, Chang's, security detail in a few episodes though they sometimes go back to AKs.
M14 Rifle
A scoped M14 rifle is seen being used by one of the US Army Special Forces members during the 3rd OVA.
Rifles
Karabiner 98k
A German soldier was seen wielding and shooting a Karabiner 98k in the flashback on the sub. Though I'm pretty sure any small arms fire inside a sub would be both loud and dangerous, but it wouldn't have mattered since the sub in the flashback was stuck.
Charleville Musket
Roberta is seen wielding a Flintlock Rifle in the OVA. It appears to be a Charleville Musket, but it is fitted with a brass patch box on the stock. It belongs to the Lovelace family for generations and Roberta takes it down and does drills with it expertly.
Sniper Rifles
Dragunov SVD
The SVD Dragunov is the sniper rifle for the Russians as Balalaika used it with expert ease when she participated in the Russian invasion of Afghanistan.
Remington 700 Sniper Rifle
Revy is seen using the Remington 700 once during episode 11. She refers to it as her Remington 700 with API ammunition. It's worth noting that Revy's two shots are fired in rather quick succession. Plus, no bolt cocking sound is heard.
VSS Vintorez
One of the Hotel Moscow soldiers was using a VSS Vintorez on Yakuza.
Gepard Anti Materiel Rifle
In the first episode, Revy busted out this rifle only once. She referred to it as her anti-tank rifle, though she never mentions what model it is.
Barrett M82
In the 3rd OVA, Roberta is seen firing a Barret M82A1 with a grenade launcher (based on an C.A.W. Airsoft Grenade Launcher) mounted underneath it with one hand.
Machine Guns
Yakushev-Borzov Yak-B
In the first two episodes, the protagonists come under attack by an Mi-24 Hind-A helicopter piloted by mercenaries hired to kill them, the Hind having a nose-mounted Yakushev-Borzov Yak-B as part of it's weaponry.
M60
The M60 was seen only in one episode introducing the character, Rico an "Apprentice Priest" with the Church of Violence. He provided support fire while his "sisters" unloaded to intruders trespassing on their "sacred grounds".
MG42
This MG42 was shown twice on the Neo-Nazi ship, fired once when Revy tried to surface. One of the leaders of the Nazis, panic when seeing Revy rampaging on the ship. When he tried to fit the belt of bullets, Revy was already behind him. The weapon was dropped when the man tried to grab a grenade, but Revy killed him.
Browning Automatic Rifle M1918A2
The Browning Automatic Rifle was one of the specialty weapons used in the series to show a more personal aspect in how an assassin and her choice of gun is. This awesome weapon of the past is used by Gretel, the girl twin of a very disturbing pair of assassins. Because it's an anime, the artists several times, drew the BAR to be extremely bigger than the user to show how freakishly strong she is. Apparently she uses the M1918A3 model introduced in 1940.
Gretel usually hides it in a cute blanket with a small teddy bear attached to the end of a string holding the whole thing together. In the first instance Gretel busted her weapon out, there was a small doll handing at the end of the sling. The BAR she uses has a more dark grey finish to it.
On the gun wall, seen in the distance, what looks like a Bren Mk. I british light machine gun is seen above the M1 Thompson. Interestingly, in the novel, the Bren is used by Revy. However, in both the anime and OVA, it is not fired, or used by any characters.
Possible M249 SAW
When Roberta drops her suitcase close to the end of the bar shootout in the episode "The Killer Maid", it opens when it hits the ground. In the split seconds the insides are visible it is possible to discern what looks to be a M249 SAW with it's ammo belt, several cylinders that may be 40mm grenades, a combat knife and an unidentified rifle at the bottom of the suitcase.
Handheld M134 Minigun
One of the members of an extra part of a large group of mercenaries hired to get Jane uses a M134 Minigun like the one in Terminator 2 hence the "Chainsaw Grip"(The Predator model had an M60 machine gun handguard instead) , to shred through a door, but in the end was defeated by the fact that it takes a split second for the barrel to spin up and fire.
Browning M2HB
During OVA 1, when calling for backup, one of the SUVs belonging to the Colombian Mafia had a Browning M2HB mounted on top of it. In the series we also see, on several occasions, twin M2HB machine guns in a tandem mount. All of these are seen aboard pirate craft chasing in episode 3 ("Ring-a-Ding ship chase").
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DShK
DShK heavy machine gun is a soviet made .50 cal Heavy Machine gun. Seen on the back of a truck fired by Hotel Moscow troops at Hensel and Gretel.
Grenade Launchers
M79 Grenade Launcher
An M79 grenade launcher was used a few times, mostly in the first couple episodes where Revy single handedly destroyed at least 6 pirate ships with her perfect aim.
Arwen 37
Twice in the series, an Arwen 37 Grenade launcher of unknown type was show it looked similar to the one in picture. The ARWEN 37 is a less-lethal launcher which fires 37 mm less-lethal rounds (foam or wooden or tear gas payload) designed for riot control. It has a 5-round rotary drum magazine. "ARWEN" is an acronym for "Anti Riot Weapon ENfield".
Originally this weapon in real life is supposed to be a less than lethal launcher that would fire tear gas among other types of less than lethal ammo, but in the series it fired actual grenades, creating large explosions.
China Lake Launcher
In the first OVA, Fabiola takes out a China Lake Launcher from her back. Hers has a folding stock. It's noted that she fires each grenade without pumping it as the real world launcher is a pump action.
One of the more common grenades in the series, the Vietnam-era M26 hand grenade is used by mercenaries to attack the Yellow Flag in the first episode. It is unclear if they are fragmentation grenades or dressed-up smoke grenades (such as the one used in Lethal Weapon) as they produce an extremely heavy amount of smoke in addition to significant concussion. Revy also possibly uses one later in the submarine against the Neo-Nazis, though it could have been an M67 hand grenade as well as her hand was obscuring the body of the grenade. Roberta also drops half a dozen of these out of her... skirt, to eliminate the Colombian gang at the Yellow Flag.
They are most likely so common due to Vietnam war surplus, like many other weapons that can be found in Roanapur.
RGD-5 Hand Grenade
Several RGD-5 hand grenades were used by Hotel Moscow troops to attack a Kosa Clan office after ties have been severed.
Rocket Launchers
BGM-71 TOW
BGM-71 TOW missile launchers are used by the Neo-Nazis on their ship they took to the South Pacific seas for their mission. The ship alone was just a research type freighter, so they wouldn't naturally have weapons against other ships. To the dismay and surprise of the Lagoon crew, the Neo-Nazis fired several of the wire-guided antitank missiles against them. The PT boat narrowly narrowly survived the attack by running until the TOW's ran out of fuel and crashed into the ocean.
RPG-7
The RPG-7 is seen in use quite a few times in the series, but was first seen used by Revy at the end of episode one when she fired a "warning shot" at a larger carrier ship to make them stop so they can rob them. In Episode 11 when given a new job by Chang, one of the attackers fired an RPG into Lagoon's apartment, making Revy shout "RPG!" in slow motion.
Seen in the used of a man who calls himself the "Torchweaver" for obvious reasons making comments that all have to deal with fire like grilling, cook outs, and BBQ. Apparently Torch has a simple looking lighter that actually spits out an amazing wall of flame and then pulls his actual M2 Flamethrower seemingly out of nowhere.