The world is overtaken with a very deadly disease that turns humans into zombies. In Japan, several students of Fujimi High School, and the school nurse, band together to survive the present apocalypse. The story follows Takashi Komuro, one of the students who survived in the initial outbreak.
The following weapons were used in the anime High School of the Dead:
Takashi and Rei find two Smith & Wesson Model 37s on a pair of dead police officers, though one has it's handle broken. Takashi later hands the revolver to Kohta to compensate for his physical weakness. Several police officers are seen firing their M37s at zombies trying to breach their roadblocks and a senior officer executes a anarchist inciting a unruly mob on live television before the officer later commits suicide with his sidearm near other officers. The author comments on how the Nambu Model 60 was no longer the official sidearm for all Japanese police officers and therefore chose the Smith & Wesson to show the unique choice of weapon for each department.
SIG Sauer P226R
In Episode 8; "The Dead Way Home", a Secret Service agent uses SIG P226Rs to gun down zombies trying to reach the wounded President and Chairman of the Joint Chiefs alongside a few remaining staff members on board Air Force One. Another staff member armed with a P226R uses it to shoot the wounded Chairman in the head after he shows signs of zombification.
Luger P08
Takagi's mother hands her daughter a Navy model Luger P08 complete with a 32 round "snail" drum magazine and a stock. It is referred to as "Luger P08's Holland colonial military model".
M1911A1
A Right Wing member (or Nationalist) is seen firing a M1911A1 at the approaching zombie horde in the final battle at the Takagi estate with the zombies.
Browning M1910
A Browning M1910 is seen in the opening sequence. Another M1910 can be seen on Takagi's mother's leg holster.
Shotguns
Remington 870
Yakuza members and several civilians are seen running amok with Remington 870s. A flashback reveals that Kohta trained with one while on vacation in the U.S. undergoing a firearm's training course.
Remington 870 Field Shotgun
Another Yakuza gang member is seen using a Remington 870 Field Shotgun with the barrel (presumably) cut down for easier handling.
Ithaca M37
A Ithaca 37 is found in Minami's household after being stolen from a firearms locker which Takashi and Kohta broke into. Kohta initially uses it as his main weapon before handing it to Takashi. Saya uses the dropped M37 to fight the zombies at the wire blockade. Takashi later uses it a melee weapon after running away from the wire blockade. It appears that the M37 is fitted with an M68 CCO. Which would explain why the Optic is disabled by the EMP due it being powered by a 3-Volt Lithium Battery.
Over and Under Shotgun
A citizen is seen firing an over and under shotgun, but fumbles in loading the shells and is promptly surrounded and devoured by zombies.
Remington M1100
A Remington Model 1100 is seen during the final episode being used by a Nationalist member.
Submachine Guns
Heckler & Koch MP5A4
Riot Police (機動隊 Kidotai) officers are seen firing Heckler & Koch MP5A4s at zombies.
A Springfield Super Match M1A is found in Minami's household with rails attached for a Surefire foregrip and an Aimpoint red dot sight. Rei handles the M1A as her main weapon. In episode 7, Takashi handles the rifle to snipe at zombies about to eat Rei. Hirano, like in the Manga, incorrectly calls it an M1A1 with the extra 1 number. There's an inconsistency with the charging handle. One scene it is shown as an incredibly oversize charging handle that can fit the size of an entire hand and then for the rest of the series, it's in its normal size.
Armalite AR-10(T)
An Armalite AR-10(T) is found in Minami's household that Kohta mistakes for a Knight's Armament SR-25 at first. Kohta uses it as his primary weapon. The author comments Minami seduced an American soldier to import the illegal rifle into Japan via the American military air service avoiding customs.
An error in the English dubbing caused Kohta to mis-identify it as a "AR-110" instead of a AR-10.
Howa Type 89
JGSDF soldiers are seen wielding Howa Type 89s as their service rifle.
M16A1
Members of the Right Wing (or Nationalist) group are seen firing M16s at the approaching zombie horde during the final battle at the Tagaki Estate in the final episode.
AK-74
A AK-74 is seen in use in Hirano's FPS game imagination.
Sniper Rifle
Heckler & Koch PSG-1
Sergeant Minami uses a Heckler & Koch PSG-1 in her role as a Special Assault Team sniper, clearing an airport of zombies wandering around its runways.
Machine Guns
Sumitomo Minimi
A Sumitomo Minimi LMG, the Japanese-licensed version of the FN Minimi, is seen mounted on a JGSDF Type 82 CBRN reconnaissance vehicle.
Sumitomo M2
A Sumitomo M2, the Japanese-licensed version of the Browning M2, is seen mounted on a JGSDF Type 10 MBT.