Resident Evil 5

H&K USP

Chris uses this weapon in the teaser trailer. It is unknown if this weapon will make the final cut. It appears to be fitted with a custom compensator.

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Chris with his custom H&K USP at the ready.

Beretta 92FS

These are Chris's and Sheva's handguns. They are featured in every screenshot that have Chris and/or Sheva in them.

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Chris with a Beretta 92FS which appears to be fitted with a compensator.

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Sheva with her Beretta 92FS with a trigger guard mounted laser.

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Sheva reloads her 92FS.

Ithaca 37ish shotgun

Chris has been shown with this weapon. Wood grips have been featured on this weapon. It is an Ithaca magazine tube cap but feattures a Mossberg 500 tang safety, making it a video game combo gun.

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Chris fires a fictional shotgun while Sheva fires her 92FS.

Remington 700

A screenshot featured in a magazine shows Sheva holding this rifle, caliber unknown.

[1]

Unknown Benelli shotgun

A picture on Wikipedia depicts Sheva posing with either a Benelli M1 or M3 Super 90 shotgun. More likely a M3.

[2]

Scorpion SA Vz. 61

Sheva is shown with this weapon strapped to her back while fighting off enemies. Caliber is unknown, more than likley .32 ACP.