The Silence of the Lambs

We can see several guns in this movie:

Smith and Wesson model 13

This .357 magnum, 3" barrel revolver was the last issue revolver of the FBI (usually loaded with .38 spl +P .158 gr LHP ammo)

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FBI recruits training in a deleted scene of "the silence of the lambs"

The holster used in the movie seems to be also the one that the FBI used with the S&W (note the Speedloader pouch)

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but, unfortunately, someone forgot to teach Jodie Foster how to holster the gun:

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"it's hard to get this thing into the holster"

The revolver used by Jodie Foster in the movie has a Pachmayr Grip adaptor (note that the bullets in the speedloader are SJHP, and not the .38 spl LSWCHP +P, used by the FBI in that era:

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Browning Hi-Power

Used by a SWAT agent:

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The silence of the lambs

Colt Government

A deactivated Colt 1911 is used during FBI instruction

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Note that the gun is deactivated (arrow)

Colt Python

The gun used by the killer is a 6" barreled Colt Python

Heckler & Koch MP5

A H&K MP5-K is seen in the hands of a FBI agent