USSS Agent Frank Horrigan (Clint Eastwood) uses a Smith & Wesson Model 19 at the start of the film to arrest Mendoza (Tobin Bell) and kill his two henchmen. Later on, A Secret Service agent holds a Model 19 on Horrigan before he disarms him.
SIG-Sauer P228
USSS Agents Frank Horrigan (Clint Eastwood) and Al D'Andrea (Dylan McDermott) carry SIG-Sauer P228 pistols as their sidearms in the film, as do all the other Secret Service Agents.
At the start of the film, Mendoza (Tobin Bell) hands Frank Horrigan (Clint Eastwood) a nickel plated Llama III-A to kill Al D'Andrea (Dylan McDermott) after he discovers he is a Secret Service agent. Frank weighs the gun as he approaches and convinces Mendoza he isn't Secret Service by clicking the gun to D'Andrea's head, aware it was in fact empty.
Composite Pistol
Mitch Leary (John Malkovich) builds a plastic Composite Pistol with two barrels as an assassination weapon to kill the President of the United States. While it is questionable how well the composite material would withstand the high pressure gases from firing, it is used several times in the film without ever breaking. When at the hotel where the President is staying, Leary assembles the weapon under the party table (after practicing assembling it blind folded several times) and had previously hidden the ammunition in a rabbit's foot keychain, and the springs in a pen. The weapon appears to use .32 Smith & Wesson Long ammunition.
IMI Uzi
When the DC Metropolitan Police attempt to arrest Mitch Leary (John Malkovich), the DC ERT officers are armed with IMI Uzi submachine guns with stocks extended. Unfortunately, it turns out that Leary scrambled the trace and lead the Secret Service and the police to a completely different address. Uzis is also seen used by the Secret Service agents when they rush the President out of the hotel after the assassination attempt.