[[Image:AMT BackupRight.jpg|thumb|none|350px|AMT 380 Backup with bare metal frame - .380 acp]]
[[Image:AMT BackupRight.jpg|thumb|none|350px|AMT Backup II - 380 with all stainless frame - .380 acp]]
[[Image:Spawn-unknown-1.jpg|thumb|none|600px|Jessica Priest's ([[Melinda Clarke]]'s) concealed weapon is revealed as she sits down]]
[[Image:Spawn-unknown-1.jpg|thumb|none|600px|Jessica Priest's ([[Melinda Clarke]]'s) concealed weapon, an AMT Backup 380 with black frame, is revealed as she sits down - .380 acp]]
When Al Simmons (Michael Jai White) is still a (human) A-6 operative and has not yet become Spawn, he is seen on several missions carrying a Heckler & Koch MP5K as his weapon of choice. In the scene where he carries out an assassination at a military air base in Hong Kong, his MP5K is fitted with a suppressor.
Heckler & Koch MP5A3
Heckler & Koch MP5A3 submachine guns are carried by many of the security guards at A-6. A guard at the air base in Hong Kong also has one.
Walther MPK
Walther MPK submachine guns are also carried by many of the A-6 security personnel.
AMT 380 Backup Pistol
When Al Simmons tells A-6 Director Jason Wynn (Martin Sheen) that he doesn't want to be an assassin anymore, Jessica Priest (Melinda Clarke) sits down on the couch in Wynn's office. She has a AMT 380 Backup Pistol concealed on her thigh beneath her skirt.
Beretta 92FS Inox (?)
While he is at A-6 talking to Jason Wynn, Al Simmons has a nickel-plated or stainless pistol in a shoulder holster. It appears to be a Beretta 92FS Inox, but this is not certain.
AKM
AKM assault rifles are carried by North Korean military personnel guarding the bio-chemical weapons plant.
Colt 9mm SMG
Jessica Priest (Melinda Clark) uses a Colt 9mm submachine gun (RO635) in the North Korean bio-chemical weapons plant; it is fitted with an flammable liquid-squirting canister under the barrel, a C-More red-dot sight, and a pair of laser sights.
(Fake) FN P90
Spawn (Michael Jai White) and various A-6 personnel are seen wielding weapons that appear to be FN P90 personal defense weapons. However, they are actually Cobray M11/9 machine pistols that have been visually modified to resemble P90s. In some scenes, the long stick-like magazines of the Cobrays can be seen protruding from beneath the weapons' grips as they are fired.
Modified Cobray M11/9
Spawn (Michael Jai White), Jessica Priest (Melinda Clark), Jason Wynn (Martin Sheen) and many of the A-6 personnel are also seen using unusual silver machine pistols in many scenes. Like the movie's fake FN P90s, these are also Cobray M11/9s that have been dressed up with movie props to appear "futuristic".
Olympic Arms OA-93
During the scene when Spawn fights the Violator (John Leguizamo), he uses an Olympic Arms OA-93 AR-15 pistol converted to full-auto and fitted with a buffer tube (a necessary modification for the weapon to fire blanks). This same prop weapon also appears in a number of other movies, including Bad Boys and Clear and Present Danger.
Armsel Striker/Street Sweeper short-barrel
During the scene in which he breaks into the A-6 armory, Spawn can be seen loading up a short-barreled, stockless version of the Armsel Striker or its American cousin, the Street Sweeper. This weapon is fitted with a red-dot sight, and it is portrayed in the film as a grenade launcher when it is used by the Clown (John Leguizamo).
M16A2
When Spawn breaks into the A-6 armory, a rack of M16A2 rifles can be seen.
Heckler & Koch HK93
In the A-6 armory, Spawn can be seen loading a magazine into a Heckler & Koch HK93 rifle (it has the non-detachable lower receiver, plus the magazine well clearly reads "HK93").
Franchi SPAS-15
When Spawn is grabbing weapons from the A-6 armory, a Franchi SPAS-15 combat shotgun can be seen on the floor amongst the weapons.
M60
M60 machine guns are used by police SWAT officers in APCs during the shootout at the Consortium gathering at the hotel.
1917 Enfield Rifle
At the hotel where Spawn crashes the Consortium party, a number of U.S. honor guard soldiers armed with either M1917 Enfield bolt-action rifles joined the A-6 personnel in shooting at Spawn while he was climbing up the outside of the hotel. The rifles appeared to be painted white and are still able to cycle and fire live ammunition. Look at the front sight it's a 1917 Enfield.
Steyr AUG
When Spawn is planning to run off and kill the Clown, he grabs a short-barreled Steyr AUG from his arsenal which is only barely seen for a second. Due to a continuity error, the weapon becomes a Mossberg 500 Bullpup as soon as he turns around to face Cogliostro, who tells him that guns are useless. When Spawn is grabbing weapons from the A-6 armory, magazines for the AUG can be seen amongst the weaponry he has scattered across the floor, but the weapon itself can only be seen for a second later in the film.
Mossberg M500 Bullpup
Twice in the film, Spawn can be seen wielding (but not firing) a Mossberg 500 Bullpup.