[[File:Sicario-mk23.jpeg|thumb|none|500px|The MK23 can be differentiated from the USP series by the raised sections of the front and rear of the slide at the point the sights are situated, from the curved underside of the front of the frame and also the threaded hole in the front of the wider, elongated trigger guard (for installation of a Wilcox or similar locking LAM unit) which you can see clearly in this still.
[[File:Sicario-mk23.jpeg|thumb|none|500px|The MK23 can be differentiated from the USP series by the raised sections of the front and rear of the slide at the point the sights are situated, from the curved underside of the front of the frame and also the threaded hole in the front of the wider, elongated trigger guard (for installation of a Wilcox or similar locking LAM unit) which you can see clearly in this still.
Also the frame on a Mark 23 is significantly wider before the integrated rail than on a USP. Though it is hard to identify in the film, this enhanced publicity still helps, as well as a brief side shot in the film, detailing the unique Mark 23 trigger guard.]]
Also the frame on a Mark 23 is significantly wider before the integrated rail than on a USP. Though it is hard to identify in the film, this enhanced publicity still helps, as well as a brief side shot in the film, detailing the unique Mark 23 trigger guard.]]
[[File:Sicario 28.jpg|thumb|none|600px|Alejandro ([[Benicio del Toro]]), while carrying his Gen 4 Glock 17, (if you look closely) can actually be seen with the Mark 23 in his vest holster. Nifty continuity and foreshadowing. Note that the Mark 23 in the vest holster could not have been mistaken for a similar USP, as it has an ambidextrous safety lever, which can clearly be seen on its left side.]]
[[File:Sicario 28.jpg|thumb|none|600px|Alejandro ([[Benicio del Toro]]), while carrying his Gen 4 Glock 17, (if you look closely) can actually be seen with the Mark 23 in his vest holster, suppressor attached. Nifty continuity and foreshadowing. This could not have been mistaken for a similar USP, as it has an ambidextrous safety lever, which can clearly be seen on its left side.]]
[[File:Sicario-mk23-1.jpg|thumb|none|601px|Alejandro confronts Fausto Alarcon (Juan Cedillo) and his family. Note the reflective H&K finish.]]
[[File:Sicario-mk23-1.jpg|thumb|none|601px|Alejandro confronts Fausto Alarcon (Juan Cedillo) and his family. Note the older style reflective H&K "Maritime" finish. New MK23s feature HK's standard "Hostile Environment" finish.]]
[[File:Sicario-mk23-2.jpg|thumb|none|601px|Alejandro brandishes the suppressed Mark 23.]]
[[File:Sicario-mk23-2.jpg|thumb|none|601px|Alejandro brandishes the suppressed Mark 23.]]
[[File:Sicario-mk23-3.jpg|thumb|none|601px|Alejandro fires the suppressed Mark 23.]]
[[File:Sicario-mk23-3.jpg|thumb|none|601px|Alejandro fires the suppressed Mark 23.]]
A Beretta 92FS can be seen in a Delta Force operator's holster during the shootout at the border crossing. A Sonora cartel member is later seen wielding a Beretta.
SIG-Sauer P226 DAK
A Sonora Cartel gunman uses a SIG-Sauer P226 DAK during the border crossing shootout.
FN Five-seveN
Manuel Diaz (Bernardo P. Sarancino) retrieves an FN Five-seveN USG when he is pulled over by the police.
Alejandro (Benicio del Toro) uses a Heckler & Koch MP5A3 with a suppressor, railed handguards and an Aimpoint sight. An unsuppressed MP5A3 with a Surefire forend is used by a cartel gunman during the border crossing shootout.
Heckler & Koch MP5SD3
Alejandro's MP5A3 becomes a Heckler & Koch MP5SD3 with an Aimpoint sight in non-firing scenes.
Kate, Reggie Wayne (Daniel Kaluuya) and Phoenix PD SWAT officers use M4A1 Carbines during a raid. DEA Agent Steve Forsing (Jeffrey Donovan) and Delta Force commandos also use M4A1 Carbines, as do Mexican Federal Police officers, Border Patrol Officers, and cartel members. Note, Prior to the convoy shootout at the border crossing, as the teams are identifying the two threat targets, Jeffrey Donovan's M4 dust cover is open and the chamber is clearly empty.
Daniel Defense M4A1
Matt (Josh Brolin) uses a Daniel Defense DDM4 "M4A1" with a foregrip, Magpul PMAG and EOTech sight as his main weapon.
Colt Model 933
A Mexican Federal Police officer is seen wielding a Colt Model 933.
G&P M4 MOE CQBR
Delta Force commandos use airsoft G&P M4 MOE CQBR rifles throughout the film. Border Patrol and ICE Agents are also seen with these rifles as they are guarding a large group of captured immigrants.
Heckler & Koch G36C
One of the Delta Force commandos can be seen wielding a Heckler & Koch G36C with an EOTech sight.
AKMSU
One of the cartel gunmen at the border crossing wields an AKMSU.
AK-103
An AK-103 rifle (likely an American semi-auto clone such as the Arsenal SLR-103) is used by a sicario disguised as a Federal police officer during a shootout. A similar rifle is also seen in Silvio's (Maximiliano Hernández) home.
AKMS (Shortened)
One of Fausto Alarcon's bodyguards uses a shortened AKMS rifle.
Remington 700 PSS
During the film's opening raid, a SWAT sniper uses a Remington 700 PSS to provide cover for Kate's team.
Machine Guns
FN M249E2 SAW
M249 SAW machine guns are mounted on Mexican Federal Police pickups.
Shotguns
Mossberg 590 Mariner Cruiser
A member of the cartel uses a Mossberg 590 Mariner Cruiser during a shootout with the FBI.